On a quiet and ancient street, the Exe Domus Aurea Hotel offers you an excellent setting, barely 200 metres from the Stazione Terminiand surrounded by the city's important icons, like the Diocletian Baths, Santa Maria degli Angeli, La Sapienza University, the Villa Borghese and its numerous museums, the Castra Prætoria, the Fountain of Trevi, the Barberini Palace and even the Piazza di Spagna. A 20-minute walk will take you to the major monuments of Rome: the Colossus, the Colosseum, the Fori Imperiali, Piazza Navona, Campo dei Fiori, the Pantheon, the Trajan Column and, on the other side of the Tiber, all the marvels of the Vatican City and the Trastevere.
One can easily reach Fiumicino airport or any other part of the city by train and metro from the Termini Station.
Set in an elegant building in 19th century, neo-classical style, the hotel is located in one of the main business and shopping areas, next to Via Corso and Via Nazionale.
More info in this link.